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This blog is intended to provide information to educate readers about molecular testing and genetic sample collection and DNA Genotek products.  Some of the information on this blog represents emerging scientific research or data developed for research purposes only. More information here.

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About DNA Genotek

Welcome to The Genetic Link, a blog providing new insights into DNA and RNA sample collection by DNA Genotek. DNA Genotek is a subsidiary of OraSure Technologies, Inc.

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Large Cohort Study Shines Light on the Fragile X Syndrome Gray Area

 
Fragile X DNA saliva Oragene

The author of this article, Lisa Gamwell, is a Sales Development Analyst at DNA Genotek.

Customer feedback – are we listening?

 
DNA Genotek customer feedback

In this recent article, we took an in-depth look at DNA Genotek’s customer service and technical support to understand why our customers value it so much.  This week, we’re examining a slightly different angle on customer feedback to illustrate how much we value what you have to say.

Genetics and post traumatic stress disorder

 
genetics post traumatic stress

Post-traumatic stress disorder (PTSD) is a type of anxiety disorder that can occur after an individual has experienced an extreme emotional trauma involving the threat of injury or death. It is not known why traumatic events cause PTSD in some people but not in others, however, factors such as genes, emotions, and family setting may all play roles.

Total protection of buffy coat samples - HEMAgene•BUFFY COAT stabilizing reagent

 
stabilize buffy coat ambient room temperature

DNA Genotek has been a leader in the biostabilization technology field for many years and throughout that time, many customers, like you, have used our Oragene product line. The expertise we have garnered in this field allowed us to transfer our knowledge of saliva collection and stabilization to address a new challenge: the ambient temperature stabilization of blood and blood components.

Using genetics to understand neurodevelopmental & psychiatric disorders

 
Ravinesh Kuman

Over the past few months, we’ve been posting a series of blog articles on the topic of genetics and mental health. This month, we have an exciting story to share with you on the growing role of genetics in understanding a range of psychiatric disorders from an institution that is breaking new ground in this important research area.

DNA Genotek’s top 10 list for 2013

 
DNA Genotek Top 10 2013

Once again, it is time for my annual review of DNA Genotek’s year and to highlight the top 10 items that I believe made an impact in 2013. Like previous years, there’s been a lot of exciting activity and choosing only 10 items is always a challenge. After much reflection, these are the 10 things that I will remember most about 2013 at DNA Genotek.

Using NGS and DNA from saliva to find needles in haystacks

 
DNA saliva Oragene

We always enjoy hearing about how our customers are using our products for innovative projects. Recently, we learned about a new project in Germany called GeneTalk, which uses Oragene to collect DNA from saliva. GeneTalk is what many physicians and scientists working on human next generation sequencing (NGS) data sets have been waiting for. We know that NGS is an effective method for identifying rare disease causing variants associated with genetic disorders and as a valuable tool for diagnosing and treating many other diseases. The challenge in analyzing the sequence variants of a patient is to discriminate between all the variants without medical relevance and the mutations that actually have an impact on the disease. Many believe that a large database of exomes from healthy controls may help to create this benchmark and thus speed up the identification of the mutations causing genetic disorders. This is where GeneTalk comes in.

A peek inside technical support and customer service at DNA Genotek

 
DNA Genotek Oragene service support

DNA Genotek is proud to provide a high level of service and support to our customers. We know that our success as a company is tightly integrated with the success of our customers and we are committed to providing access to a team of skilled scientists and creative resources to optimize genetic projects[1] from sample collection through to downstream processing.

The origin and impact of the DISC1 gene: From schizophrenia to ADHD

 
DNA saliva, genetics, ADHD

While reading a recent publication in the American Journal of Human Genetics Part B entitled DISC1 in Adult ADHD Patients: An Association Study in Two European Samples [1], I was immediately intrigued by the first sentence of the abstract: “The DISC1 gene was named after its discovery in a Scottish pedigree with schizophrenia (SCZ) patients.” [1] This inspired me to do a little background reading regarding the discovery of the DISC1 gene and, as it turns out, it’s a pretty interesting story. Therefore, for the third blog in our Genetics and Mental Health Series, I would like to tell you how this curious gene came to be associated with ADHD.

Gene-by-environment interactions: When nature and nurture collide

 
DNA saliva for psychiatry genetics

Last month we posted our first blog article in the Genetics and Mental Health Series.  We discussed incorporating genetic analysis into research programs to uncover differences in traits and diseases, or to potentially improve the diagnosis and treatment of patients. This month we would like to expand on that idea by exploring how our traits and personality characteristics are controlled by two things: our environment and our genetics. A person’s genes and their environment interact to affect their mental health and behaviour, and this interaction, referred to aptly as the gene-by-environment interaction, is a very interesting, if challenging, area of research. 

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