Genetic epidemiology, the study of how genetics contribute to health and disease in families and populations, seeks to derive a statistical analysis of how genetics works in large groups. It therefore requires enough DNA samples from a given population to reduce the effect of outliers and ultimately, determine objective truths.Read More
DNA Genotek's Sample Collection Blog
The Centers for Disease Control and Prevention (CDC) estimated in 2012 that 1 in 68 children in the US have autism spectrum disorder (ASD), (1 in 42 boys and 1 in 189 girls) . The prevalence of ASD has increased significantly over the past two decades and, while this may be attributed to better diagnostics and an increased awareness, it means we simply do not know enough about the cause(s) of autism and how to best improve the lives of those people living with this condition. While there are some treatments available, such as behavioral therapy, there are no approved medications to treat the core symptoms of autism.Read More
Personal genomics is a branch of human genomics focused on sequencing and analyzing the unique genome of an individual to help determine optimal healthcare decisions… at least that is where it began. Today, there are companies adopting personal genomics to provide individuals with information on a range of topics from ancestry, diet, athletic training and even optimized wine selection.Read More
Dr. Gerardo Jimenez Sanchez is a fundamental and prominent figure in the development and expansion of human genomics in Mexico. His accomplishments are equally impressive as they are extensive:
We often profile customers who are working on particularly interesting genetic research projects on The Genetic Link, in the hope that it will benefit other customers. Dr. Nasir Ali Afsar MBBs, M.Phil, Ph.D. from the College of Medicine at Alfaisal University in Saudi Arabia is one such researcher with a project we thought was worth sharing.
The price associated with blood collection may be perceived to be free for many institutions that have established blood collection labs/service centers; however, there are real costs to sample collection even within these environments. Phlebotomists, lab technicians, medical supplies, and shipping requirements (dry ice, containers, and overnight delivery) add to an estimated $40 per sample, not including freezer storage1. Oragene, in comparison, comes in a variety of formats with differing yield and stability capabilities which cost between 48% - 80% less. More savings are introduced as Oragene products enable at-home collection, standard shipping via regular mail at room temperature and zero refrigeration.
Welcome to the second article in a 3 part series discussing whether or not saliva can replace blood for DNA collection and analysis. In part 1 of this blog series, we examined the quality issue of blood and saliva. In part 2, we look at the functionality and ease of use. We hope you find this content interesting. Let us know what you think of this series by leaving a comment. Thank you in advance.
Affymetrix stated in a recent poster, entitled Comparison of high density genotyping results from saliva and blood samples on Affymetrix GeneChip® GenomeWide SNP 6.0 arrays, “Blood has proven a very consistent and reliable source of genetic material for many avenues of testing and research, but it can also be a time consuming, expensive and invasive collection ... Finding a comparable source of genetic material, such as saliva, that is more cost effective, more stable and less invasive would be extremely beneficial to the scientific community.”1
The first step in all genetic research and testing is obtaining a reliable DNA sample. The time and effort required to access donors and the high costs of downstream analysis make each DNA sample a very precious commodity. Confidence in sample quality and performance is of utmost importance. So, what measures confidence in a DNA sample? High quantity and high quality DNA. DNA quantity and quality are expected to be high in a blood sample however this method often presents challenges. The invasive nature of a blood draw reduces donor compliance, increases the complexity and cost required for collection, shipping and storage of samples.