Methylated cytosine, also known as “the fifth base of DNA” has attracted a lot of research attention lately due to its importance in controlling gene expression. This fifth base has inspired researchers to study its impact on several diverse fields, such as oncology, neurology, psychology, forensics and even workplace health and safety. Methylated cytosine has even been used as a predictor of biological age .In this blog post I’d like to share a few examples of the exciting ways this “extra” base is providing new avenues for research.Read More
DNA Genotek's Sample Collection Blog
While reading a recent publication in the American Journal of Human Genetics Part B entitled DISC1 in Adult ADHD Patients: An Association Study in Two European Samples , I was immediately intrigued by the first sentence of the abstract: “The DISC1 gene was named after its discovery in a Scottish pedigree with schizophrenia (SCZ) patients.”  This inspired me to do a little background reading regarding the discovery of the DISC1 gene and, as it turns out, it’s a pretty interesting story. Therefore, for the third blog in our Genetics and Mental Health Series, I would like to tell you how this curious gene came to be associated with ADHD.
Last month we posted our first blog article in the Genetics and Mental Health Series. We discussed incorporating genetic analysis into research programs to uncover differences in traits and diseases, or to potentially improve the diagnosis and treatment of patients. This month we would like to expand on that idea by exploring how our traits and personality characteristics are controlled by two things: our environment and our genetics. A person’s genes and their environment interact to affect their mental health and behaviour, and this interaction, referred to aptly as the gene-by-environment interaction, is a very interesting, if challenging, area of research.