DNA Genotek's Microbiome Collection and Stabilization Blog

Collect and stabilize gut microbiota samples from IBD patients undergoing dysbiosis

Posted by Erin Carpenter on Nov 6, 2018 1:26:42 PM

In human gut microbiome studies, the logistics of immediately freezing and transporting collected stool samples on dry ice is not always feasible - especially with at-home collections. If the samples are not immediately stabilized, taxonomic profile changes can occur rapidly at room temperature. Furthermore, a challenge with collecting samples from patients exhibiting symptoms of inflammatory bowel disease (IBD) or Crohn’s and chronic colitis, is stool samples can be liquid (Bristol stool type 6 and 7), complicating collection and sample handling, as well as causing a barrier to donor enrolment. To facilitate large cohort studies and produce high quality data, researchers need to be equipped with the most effective tools to easily collect, stabilize and store precious samples.

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Tags: feces collection, gut microbiome research, microbiome sample collection

How critical is it to stabilize and standardize the microbiome profile?

Posted by Megan McGrath on Feb 15, 2017 9:46:00 AM

One of the most critical components of studying the microbiome is ensuring you have a profile that is representative of the microbial community present in the donor. The reality of microbiome research, and any research for that matter, is that a variety of factors can impact the quality of your sample and its microbial community and thus, the quality of your data. Assume for example, that the microbial profile resembles Diagram “A” when in the in vivo state. The goal is to minimize any potential source of variability so that your sample accurately reflects that of the in vivo state (Diagram B) rather than an “ex vivo” artefact (Diagram C). Think of it like this: you could take a “snapshot” of the microbial community at the time of collection, preserve it through the analysis and generate an accurate microbiome profile.

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Tags: microbiome, feces collection, microbiome stabilization, microbiome collection, gut microbiome, microbiome snapshot

Advancing microbiome discoveries: An update on our grant winners

Posted by Megan McGrath on May 2, 2016 10:49:07 AM

Last year, DNA Genotek launched its first Gut Microbiome Grant program. The program attracted many applicants from varying fields of research and three winners were selected. It’s been a few months since we announced the winners, and we wanted to provide an update on their projects.  

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Tags: microbiome, feces collection, gut microbiome, omnigene gut

The intricacies of reliable microbiome collection

Posted by Stefanie Bolduc on Mar 25, 2015 11:44:38 AM

In our previous blog post, we examined the importance of preserving the microbial profile of fecal samples for microbiome analysis. But how do we ensure the sample collection method is reliable enough to attain an excellent profile? And, what are the challenges to getting a reliable sample? Let’s have a look.

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Tags: microbial dna, feces collection, microbiome collection, microbiome snapshot

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This blog is intended to provide information to educate readers about microbiome sample collection, stabilization and DNA Genotek products. Some of the information on this blog represents emerging scientific research or data developed for research purposes only. More information here.

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About DNA Genotek

Welcome to The Microbiome Snapshot, a blog providing new insights into microbiome sample collection and stabilization by DNA Genotek. DNA Genotek Inc. is a subsidiary of OraSure Technologies, Inc.

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