The first step in all genetic research and testing is obtaining a reliable DNA sample. The time and effort required to access donors and the high costs of downstream analysis make each DNA sample a very precious commodity. Confidence in sample quality and performance is of utmost importance. So, what measures confidence in a DNA sample? High quantity and high quality DNA. DNA quantity and quality are expected to be high in a blood sample however this method often presents challenges. The invasive nature of a blood draw reduces donor compliance, increases the complexity and cost required for collection, shipping and storage of samples.