DNA Genotek's Sample Collection Blog

DNA Genotek’s Top 10 List for 2012

Posted by Ian Curry on Tue, Jan 08, 2013 @ 10:01 AM

Each year I look forward to the task of reflecting on the year gone by and coming up with a top 10 list that represents highlights of the year for DNA Genotek, our customers and the health community. It was 2009 when I sat down to write the first version of this list and each year, it is one of our most popular blog articles. It is often difficult to choose the items that make this list – mostly because there are so many exciting developments to talk about. The items that made the list this year are some of the most interesting I’ve written about as I believe many of them will change the way we look at genomics in the future. I won’t be surprised if some of them also appear on top 10 lists in the coming years as several of them have some serious staying power. I hope you enjoy DNA Genotek’s top 10 list for 2012.

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Tags: DNA kit, next generation sequencing, Oragene, DNA from saliva, genetic disease, genotyping

France takes to the street to collect DNA samples for HLA registry

Posted by Dominique Fizet on Tue, Oct 16, 2012 @ 10:10 AM

The Genetic Link welcomes guest blog authors. This guest submission is from Dominique Fizet of the l'Établissement français du sang (EFS), Aquitaine-Limousin, Ă  Bordeaux. We welcome Dominique as a guest author and we hope you enjoy this article.

France’s national agency for bone marrow transplants, the France Greffe de Moelle Registry, manages bone marrow donors from all over France, which currently numbers over 200,000. To many people, this number seems large. To those in need of a bone marrow transplant, the number can be insufficient. Each year, 2000 people in France with serious blood diseases (leukemia, lymphoma) can be treated with a bone marrow transplant, giving these patients an additional chance of recovery. The demand for bone marrow transplants grows each year and with the chance of a match between a donor and recipient at 1 in one million (and more difficult for certain ethnicities), an even larger database of donors is required to meet demand.

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Tags: DNA from blood, DNA from saliva, HLA, HLA typing

How to choose the right platform for high-throughput DNA extraction

Posted by Krystin Colley on Wed, Sep 26, 2012 @ 14:09 PM

We recently published an article highlighting how to choose the best method for low-throughput DNA extraction for Oragene samples. Today, we examine various options for high-throughput DNA extraction. High-throughput DNA extraction uses an automated, robotic system to provide researchers and clinicians with high quality genomic DNA. The main advantages of this method are less hands-on time, higher consistency and reduced probability for manual errors. High-throughput extraction is generally preferred when there are a large number of samples to be processed, however whether processing a small or a very large number of samples, automation is a great way to gain efficiencies and consistency in results.

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Tags: DNA preparation, DNA from saliva, DNA purification, DNA extraction

Natural selection in high altitude: Oragene functions as an enabler for challenging field research

Posted by Nicholas Ramdass on Tue, Aug 14, 2012 @ 11:08 AM

Rookie mistakes – they will occur. I remember the first time I tried to reach out to Dr. Cynthia Beall, Distinguished Professor of Anthropology at Case Western Reserve University; it was my first year selling Oragene kits to US researchers, and still in the midst of trying to figure out the key genetic researchers in my territory, I clumsily attempted to sell to Dr. Beall. She quickly reminded me that she needed no introduction to the benefits of Oragene, describing herself as the collection kit’s “poster child” having used the product for multiple projects in the past. Yes, my rookie mistake indeed. 

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Tags: DNA collection, DNA from saliva

Can saliva replace blood for DNA collection and analysis? (Part 2 of 3)

Posted by Kerry Chatburn on Tue, Jul 17, 2012 @ 11:07 AM

Welcome to the second article in a 3 part series discussing whether or not saliva can replace blood for DNA collection and analysis. In part 1 of this blog series, we examined the quality issue of blood and saliva. In part 2, we look at the functionality and ease of use. We hope you find this content interesting. Let us know what you think of this series by leaving a comment. Thank you in advance.

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Tags: DNA collection, DNA saliva, DNA from blood, DNA from saliva, DNA children

Can saliva replace blood for DNA collection & analysis? (Part 1 of 3)

Posted by Kerry Chatburn on Thu, Jul 12, 2012 @ 11:07 AM

Welcome to the first article in a 3 part series discussing whether or not saliva can replace blood for DNA collection and analysis. We hope you find this content interesting. Let us know what you think of this series by leaving a comment. Thank you in advance.

Affymetrix stated in a recent poster, entitled Comparison of high density genotyping results from saliva and blood samples on Affymetrix GeneChip® GenomeWide SNP 6.0 arrays, “Blood has proven a very consistent and reliable source of genetic material for many avenues of testing and research, but it can also be a time consuming, expensive and invasive collection ... Finding a comparable source of genetic material, such as saliva, that is more cost effective, more stable and less invasive would be extremely beneficial to the scientific community.”1

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Tags: DNA from blood, DNA from saliva, DNA quality

Saliva samples as a source of DNA for high throughput genotyping

Posted by Shauna White on Tue, Jul 03, 2012 @ 10:07 AM

The BMC Medical Genomics Journal recently published the results of a study titled “Saliva samples are a viable alternative to blood samples as a source of DNA for high throughput genotyping”. The study examined the feasibility of collecting DNA from saliva as a non-invasive, economical substitute to DNA from blood samples for use on genome-wide arrays. The two arrays used for the study were the Applied Biosystems Taqman™ and Illumina BeadChip arrays.

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Tags: genetic research, DNA from saliva, DNA in saliva, breast cancer

DNA from saliva boosts biobank numbers

Posted by Shauna White on Tue, May 29, 2012 @ 10:05 AM

One of the biggest challenges in epidemiological research is study size - studies of very large groups of people are needed to ensure that results are statistically significant. Large numbers of participants must be recruited to provide DNA samples and consistent collection of phenotypic and environmental information is also often required. The centralized biobank at the Karolinska Institutet (KI) is an organization that has been very successful in recruiting participants despite these challenges.

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Tags: DNA saliva, DNA from saliva, Biobank

DNA from saliva boosts recruitment for PROCAS study

Posted by Shauna White on Wed, Jan 25, 2012 @ 11:01 AM

Professor Gareth Evans of the University of Manchester is heading up a major research study, which is being carried out throughout Greater Manchester. 60,000 women are being invited to join a study, named PROCAS, which aims to predict breast cancer risk for women who attend routine NHS breast screening in Greater Manchester. A woman’s risk is assessed by collecting extra information on each of the most important breast cancer risk factors – family history, lifestyle factors, breast density and genetics.

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Tags: Oragene, DNA from saliva, breast cancer, cancer research

It’s Movember at DNA Genotek

Posted by Shauna White on Tue, Nov 01, 2011 @ 16:11 PM

“Movember” (the month formerly known as November) is a moustache growing charity event held throughout November each year that raises funds and awareness for men's health. Movember is responsible for the sprouting of moustaches on thousands of men’s faces around the world. Since its humble beginnings in Melbourne Australia, Movember has grown to become a truly global movement inspiring more than 1.1 Million Mo Bros and Mo Sistas to participate, with formal campaigns in Australia, New Zealand, the US, Canada, the UK, Finland, the Netherlands, Spain, South Africa and Ireland. In addition Mo Bros and Mo Sistas support the campaign and men’s health cause across the globe, from Russia to Dubai, Hong Kong to Antarctica, Rio de Janeiro to Mumbai, and everywhere in between.

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Tags: DNA from saliva, DNA in saliva, cancer research

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This blog is intended to provide information to educate readers about molecular testing and genetic sample collection and DNA Genotek products.  Some of the information on this blog represents emerging scientific research or data developed for research purposes only. More information here.

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Welcome to The Genetic Link, a blog providing new insights into DNA and RNA sample collection by DNA Genotek. DNA Genotek is a subsidiary of OraSure Technologies, Inc.

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