At DNA Genotek, we recently learned the details of study being conducted by Generation Scotland called The Scottish Family Health Study. We wanted to share some of this information with you here on The Genetic Link.
DNA Genotek's Sample Collection Blog
Beckman Coulter Genomics has developed a new version of their DNAdvance System specifically for use with DNA Genotek’s Oragene samples. DNAdvance SP, from Beckman Coulter Genomics, is an extraction kit for the isolation and purification of DNA from saliva samples collected with Oragene self-collection Kits. The high throughput genomic DNA (gDNA) isolation reagent system enables the purification of high quality DNA from saliva samples, making it ideal for genotyping applications (SNP, fragment analysis), sequencing and qPCR. The system provides researchers and laboratories with an optimized and robust solution for DNA extraction and purification from saliva collected with Oragene kits.
A few weeks ago, I posted an article about best practices for long term storage of unpurified Oragene•DNA samples on The Genetic Link. The response to the article was positive so I'm following up with today's story about long term storage of DNA purified from Oragene•DNA samples. The preservation and storage of DNA is an important consideration for molecular epidemiology and population studies. As the makers of the Oragene•DNA family of products, we have prepared these recommendations for the long-term storage of DNA purified from saliva samples collected with Oragene to help our customers achieve optimal results.
Today, DNA Genotek announced our involvement in a significant pilot project with the UK's largest bone marrow registry, the Anthony Nolan Trust. The details of this exciting project follow:
DNA Genotek, a leading provider of products for biological sample collection, stabilization and preparation, today announced that The Anthony Nolan Trust, the UK's largest bone marrow donor registry, has selected Oragene•DNA for a pilot project aimed at increasing donor recruitment. Bone marrow donor registries, also known as HLA registries, use HLA DNA testing to match leukemia patients with prospective donors. The pilot project will determine if donor recruitment can be increased significantly with the use of non-invasive, saliva-based DNA collection compared to blood collection.
At the department of Anthropology and Genetics Institute at the University of Florida, we study genetic variation in modern human populations to answer diverse questions ranging from the route early humans took when they first migrated out of Africa to the underlying causes of racial differences in susceptibility to complex diseases. To explore these varied aspects of human evolutionary history, we spend a lot of time figuring out how to collect DNA from a large number of volunteers. With today's genetic technology, all that's necessary is to obtain a small blood or saliva sample from each of our participants -- a task relatively easy to do in concept but quite a bit more challenging in practice.
This morning, Clinical Reference Laboratory (CRL) announced that it has completed validation testing of DNA Genotek's Oragene/saliva collection kits and will adopt Oragene for use with its molecular diagnostic services.
For the second year in a row, DNA Genotek will be collecting DNA samples onsite at the National Walk for Epilepsy on March 27th, 2010 in Washington, DC. Our participation in this event supports the efforts of the Columbia University Family Studies in Epilepsy Program and their study which is designed to identify genes that play a role in causing epilepsy.
Recent statistics suggest cancer mortality rates are declining due to better prevention, early detection methods and improved treatments, yet so much remains to be done. With cutting-edge research continually pushing the boundaries of science and discovery, it is not surprising that an increasing number of cancer researchers are turning to the newest tool in the DNA collection toolbox - DNA from saliva.
This morning, BioServe Biotechnologies announced that they have completed validation testing of the Oragene/saliva collection kits and have joined DNA Genotek's Partner Program. Now, BioServe can offer customers a comprehensive testing platform for extraction and genetic analysis for Oragene/saliva samples. BioServe has validated Oragene kits for use within its DNA extraction and genotyping service, including sample quantification and normalization; whole genome amplification; multiplex-based genotyping, expression analysis and sample archiving.
Every day, it seems, scientists learn something new about how our genes work. One fascinating area of research involves understanding the role of our genes in the initiation, progression and treatment of diseases; such as cancer. Understanding cancer on a molecular and genetic level makes for good science and good medicine. We understand that all cancers are not created equally. From the moment you are conceived, your genes may increase your susceptibility to developing certain cancers or, later on, your environmental exposures or other factors may cause changes in your genes that cause cancer to develop. Cancer is not one disease, but many, adding to the complexity and breadth of studies.