DNA Genotek's Sample Collection Blog

Spoiler for ASHG 2016

Posted by Debra Ereaut on Thu, Oct 06, 2016 @ 15:10 PM

Our excitement is growing as we quickly approach the American Society of Human Genetics (ASHG) meeting in Vancouver, Canada from Oct 18th – 22nd. With so many events scheduled, we understand the importance of early planning to get the most from attending the conference. This blog article highlights our events – and we hope you add one or many of them to your ASHG agenda.

Read More

Tags: DNA saliva, Oragene, OMNIgene, gut microbiome, ASHG

Customer feedback means action

Posted by Brian Smith on Tue, Feb 09, 2016 @ 10:02 AM

It is a new year and we are excited to share what changes we made as a result of your feedback in 2015. Your suggestions kept us busy, so let us take a few moments to present several highlights.

Read More

Tags: DNA saliva, microbiome, Oragene, genomic services, OMNIgene, GenoFIND, gut microbiome

Customer updates - survey says?

Posted by Ian Curry on Mon, Jun 22, 2015 @ 13:06 PM

Once again, it is time for our Customer Satisfaction Survey blog updates. To quickly recap, if you are new to our Customer Satisfaction Surveys, we send very brief post-purchase surveys (3 questions) to capture your suggestions and overall experience with us. Through this blog, we then share updates on actions we are taking based on your feedback. To read the previous related blog articles, use these links: (Customer feedback- are we listening? And DNA Genotek’s latest changes based on your feedback)

Read More

Tags: DNA saliva, Oragene, OMNIgene, gut microbiome

How and why to integrate the microbiome into your research

Posted by Megan McGrath on Wed, Apr 15, 2015 @ 13:04 PM

So, you’ve just completed your latest human genomics research study and you’re waiting to hear if it has been accepted for publication. In the meantime, you’ve been exploring other hypotheses for health conditions and are interested in the growing field of microbiome and metagenomics research. According to a recent review, genetics explains ~20-50% of observed ‘heritability’ of medically important traits[i] but you’re interested in learning more about what makes up ‘the other 50%’. The dynamic microbiome is impacted by our daily activities and our environment (diet, exercise, sleep etc.) plays an important role in the etiology of chronic diseases not accounted for in GWAS. But there are a few items of interest that have delayed your decision to initiate a microbiome study. At the top of the list is how easy is it to integrate a microbiome study into your workflow? Is your lab set up to take on such a project? And what about the downstream applications and analysis. How different is it from SNP genotyping or whole genome sequencing? You also have to consider that you are used to working with saliva or blood and now you have to get familiar with a new sample type (and possibly an unpleasant one) – like feces.  All these questions are getting into the ‘meat’ of things you consider when taking on your first microbiome project. But let’s back up a little and look at the big picture and find out why the microbiome is an interesting study area to pursue in the first place. Why all this fuss over some microbes? 

Read More

Tags: microbiome, microbiome collection, gut microbiome

How critical is it to stabilize & standardize the microbiome profile?

Posted by Megan McGrath on Wed, Feb 18, 2015 @ 10:02 AM

One of the most critical components of studying the microbiome is ensuring you have a profile that is representative of the microbial community present in the donor. The reality of microbiome research, and any research for that matter, is that a variety of factors can impact the quality of your sample and its microbial community and thus, the quality of your data. Assume for example, that the microbial profile resembles Diagram “A” when in the in vivo state. The goal is to minimize any potential source of variability so that your sample accurately reflects that of the in vivo state (Diagram B) rather than an “ex vivo” artefact (Diagram C). Think of it like this: you could take a “snapshot” of the microbial community at the time of collection, preserve it through the analysis and generate an accurate microbiome profile.

Read More

Tags: microbiome, gut microbiome, microbiome snapshot

Subscribe to our blog

Request free trial kits of any DNA Genotek product.

Request free trial kits

Disclaimers

This blog is intended to provide information to educate readers about molecular testing and genetic sample collection and DNA Genotek products.  Some of the information on this blog represents emerging scientific research or data developed for research purposes only. More information here.

Follow us

About DNA Genotek

Welcome to The Genetic Link, a blog providing new insights into DNA and RNA sample collection by DNA Genotek. DNA Genotek is a subsidiary of OraSure Technologies, Inc.

Browse by Tag