A fascinating area of research that has been gaining a lot of momentum concerns the influence of our microbiome with overall health and disease. The human microbiome encompasses the totality of microbes, their genetic elements and their environment. Studies have shown an association between the human oral microbiota and risk of chronic diseases, such as cardiovascular disease, diabetes, obesity and certain cancers. There are many factors that influence microbial populations, such as dietary factors, exposure to pathogenic organisms and overall health status. The relationship between the host and its resident commensal and pathogenic organisms is complex and dynamic; and an exciting area of science with so much yet to be discovered.
DNA Genotek's Sample Collection Blog
Some researchers studying infectious diseases will use frozen whole mouth fluid (WMF) as a sample type for collecting microbial DNA. Storage of viable samples requires a modern lab infrastructure with cold storage and DNA from frozen WMF can be difficult to extract. In any low resource setting such as in developing countries, cold storage is a scarce resource and high ambient temperatures prevail. In addition, collections may occur in rural areas away from processing laboratories making traditional sample collection methods a challenge. Recently, a team of researchers undertook a study designed to evaluate DNA from saliva collected with OMNIgene™•DISCOVER for infectious disease sampling, allowing for easy collection, reliable transport and stabilization with no sample degradation.