DNA Genotek's Sample Collection Blog

Could microRNA from saliva be a predictor of concussion symptoms in children?

Posted by Shauna White on Thu, Nov 30, 2017 @ 14:11 PM

The issue of concussions has attracted considerable media coverage in recent years. According to the Centers for Disease Control and Prevention, 153 people in the United States die every day from traumatic brain injuries (TBI) that include concussions. Those who survive can face effects that last a few days, or the rest of their lives. Effects of concussions can include impaired thinking or memory, movement, sensation (e.g., vision or hearing), or emotional functioning (e.g., personality changes, depression). In 2013,[1] about 2.8 million TBI-related emergency department visits, hospitalizations, and deaths occurred in the United States.

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Tags: RNA, RNA saliva, miRNA, Oragene RNA

DNA Genotek’s top ten list for 2011

Posted by Ian Curry on Fri, Jan 06, 2012 @ 11:01 AM

It’s that time of year again when I reflect on the past year and highlight DNA Genotek’s top ten list for 2011. This is now the third installment of my annual top ten list series and each year, I am surprised at how difficult it is to keep this list to just ten items. I easily come up with 20 to 30 topics that could be on this list and struggle to choose those most deserving of a mention. This year, there were many significant events for DNA Genotek. After much deliberation, here is my top ten list for 2011, in no particular order.

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Tags: DNA collection, DNA, DNA saliva, Oragene, genetic research, personalized medicine, RNA

DNA from saliva to identify biomarkers predicting nicotine dependence

Posted by Shauna White on Thu, Jul 07, 2011 @ 10:07 AM

Cigarette smoking remains a leading cause of preventable disease and premature death in many countries. The chance that a lifelong smoker will die prematurely from complications due to smoking is approximately 50%[1]. There is an increasing interest in understanding the genetic link to nicotine dependence in order to better predict who is at risk and what steps can be taken to mitigate that risk. In a collaborative effort, scientists at Oregon Research Institute and SRI International  are studying the interaction between specific candidate genes associated with the stress/reward pathway and both early life adversity and ongoing life stress.  The investigators are also seeking to identify salivary biomarkers of life stress, comparing those who have experienced high life stress with those who have experienced little, through an analysis of an individuals’ RNA. This may help to explain the success or failure of interventions designed to prevent the initiation of tobacco use and the progression to nicotine dependence.

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Tags: DNA collection, saliva DNA, DNA from saliva, RNA collection, RNA

Oragene•RNA measures variability in gene expression for VITO

Posted by Shauna White on Mon, Feb 14, 2011 @ 13:02 PM

This morning, DNA Genotek announced an exciting piece of news. Our Oragene•RNA kit has been selected by VITO (Flemish Institute for Technological Research), for a series of biomonitoring research projects. Human biomonitoring campaigns study the impact of environmental stressors (pollutants, irradiation, psychological stress, etc.) on health and well-being by measuring a suite of biomarkers. Gene expression has proven to be useful to identify molecular changes in blood that relate to environmental stress. VITO will explore the value of saliva gene expression in biomonitoring and investigate the potential to develop new saliva biomarkers.

The Oragene•RNA Kit is the only all-in-one system for the collection, stabilization and transportation of high quality mRNA from saliva. It is designed for human mRNA expression profiling. VITO has chosen Oragene•RNA for the following proof-of principle projects:

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Tags: RNA, gene expression

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This blog is intended to provide information to educate readers about molecular testing and genetic sample collection and DNA Genotek products.  Some of the information on this blog represents emerging scientific research or data developed for research purposes only. More information here.

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About DNA Genotek

Welcome to The Genetic Link, a blog providing new insights into DNA and RNA sample collection by DNA Genotek. DNA Genotek is a subsidiary of OraSure Technologies, Inc.

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