Cigarette smoking remains a leading cause of preventable disease and premature death in many countries. The chance that a lifelong smoker will die prematurely from complications due to smoking is approximately 50%. There is an increasing interest in understanding the genetic link to nicotine dependence in order to better predict who is at risk and what steps can be taken to mitigate that risk. In a collaborative effort, scientists at Oregon Research Institute and SRI International are studying the interaction between specific candidate genes associated with the stress/reward pathway and both early life adversity and ongoing life stress. The investigators are also seeking to identify salivary biomarkers of life stress, comparing those who have experienced high life stress with those who have experienced little, through an analysis of an individuals’ RNA. This may help to explain the success or failure of interventions designed to prevent the initiation of tobacco use and the progression to nicotine dependence.
DNA Genotek's Sample Collection Blog
Since the inception of DNA Genotek, we have been driven to enable significant worldwide health improvements and to create a loyal community of customers. In our early days, we learned from customers that DNA and RNA collection can be challenging. With an aim to facilitate easier collection, we worked closely with customers to solve these challenges with thoughtful product design and a focus on ease of sample collection. Our customers tell us we've done this successfully with our Oragene family of saliva-based DNA and RNA collection products.