At DNA Genotek, we are continually being introduced to new and exciting research projects through the innovative work of our customers. I recently came across a particularly interesting study which is known as one of the largest metastatic breast cancer studies to date. The study, led by the Broad Institute of MIT and Harvard University, is called the Metastatic Breast Cancer (MBC) Project. This project caught my attention because of their unique approach to patient recruitment and engagement which is garnering media coverage across the country.Read More
DNA Genotek's Sample Collection Blog
In the summer of 2011 we wrote about an exciting project out of the United Kingdom that selected Oragene collection kits for a study that aimed to unlock genetic changes behind development disorders. The Deciphering Developmental Disorders (DDD) study is a direct collaboration with all twenty-three of the NHS Clinical Genetics Services from across the UK together with the Wellcome Trust Sanger Institute.
Since the launch of The Genetic Link blog back in 2009, we’ve shared dozens of stories from the field highlighting remote DNA collections, innovative approaches to research, and unique event-based collections. Each of these stories was based on a research team searching for the gene or genes responsible for a particular disease or health condition. The story in this article is unique in that it highlights a project that is hoping to attract individuals who are willing to share their personal genome, health information and trait data for a broader application. The goal is to advance scientific progress by inviting willing participants to share their personal genetic data for the greater good.
We always enjoy hearing about how our customers are using our products for innovative projects. Recently, we learned about a new project in Germany called GeneTalk, which uses Oragene to collect DNA from saliva. GeneTalk is what many physicians and scientists working on human next generation sequencing (NGS) data sets have been waiting for. We know that NGS is an effective method for identifying rare disease causing variants associated with genetic disorders and as a valuable tool for diagnosing and treating many other diseases. The challenge in analyzing the sequence variants of a patient is to discriminate between all the variants without medical relevance and the mutations that actually have an impact on the disease. Many believe that a large database of exomes from healthy controls may help to create this benchmark and thus speed up the identification of the mutations causing genetic disorders. This is where GeneTalk comes in.
Beckman Coulter Genomics has developed a new version of their DNAdvance System specifically for use with DNA Genotek’s Oragene samples. DNAdvance SP, from Beckman Coulter Genomics, is an extraction kit for the isolation and purification of DNA from saliva samples collected with Oragene self-collection Kits. The high throughput genomic DNA (gDNA) isolation reagent system enables the purification of high quality DNA from saliva samples, making it ideal for genotyping applications (SNP, fragment analysis), sequencing and qPCR. The system provides researchers and laboratories with an optimized and robust solution for DNA extraction and purification from saliva collected with Oragene kits.