Welcome to the second article in a 3 part series discussing whether or not saliva can replace blood for DNA collection and analysis. In part 1 of this blog series, we examined the quality issue of blood and saliva. In part 2, we look at the functionality and ease of use. We hope you find this content interesting. Let us know what you think of this series by leaving a comment. Thank you in advance.
DNA Genotek's Sample Collection Blog
Affymetrix stated in a recent poster, entitled Comparison of high density genotyping results from saliva and blood samples on Affymetrix GeneChip® GenomeWide SNP 6.0 arrays, “Blood has proven a very consistent and reliable source of genetic material for many avenues of testing and research, but it can also be a time consuming, expensive and invasive collection ... Finding a comparable source of genetic material, such as saliva, that is more cost effective, more stable and less invasive would be extremely beneficial to the scientific community.”1
The first step in all genetic research and testing is obtaining a reliable DNA sample. The time and effort required to access donors and the high costs of downstream analysis make each DNA sample a very precious commodity. Confidence in sample quality and performance is of utmost importance. So, what measures confidence in a DNA sample? High quantity and high quality DNA. DNA quantity and quality are expected to be high in a blood sample however this method often presents challenges. The invasive nature of a blood draw reduces donor compliance, increases the complexity and cost required for collection, shipping and storage of samples.