It is widely accepted that genetic factors are strongly linked with athletic performance. After receiving my own 23andMe wellness results, I learned that I was a carrier of the speed gene-- α-Actinin-3 (ACTN3) R577X polymorphism -- which is known to be common in elite power athletes. According to 23andMe, at national and international levels of athletic competitions, this gene seems to make a difference when it comes to athletes’ success.Read More
DNA Genotek's Sample Collection Blog
Many researchers have asked the question: can saliva replace blood for DNA collection and analysis? Research studies confirm that DNA from saliva is equivalent to DNA from blood for analysis; however, when it comes to maximizing research budgets it is also important to consider the costs of the sample type you are using.Read More
“Diabetes is the fastest growing debilitating disease in the world”.
Dr. Al-Anouti and Dr. Al-Safar
In 2015, statistics showed that 415 million people suffer from diabetes worldwide. The rate is expected to increase by 54.5% and reach about 642 million people by 2040. The Middle Eastern population account for approximately 20% of these cases. According to the International Diabetes Federation (IDF), the United Arabian Emirates (UAE) has 745,940 diabetics, 304,000 undiagnosed diabetics, and 934,300 pre-diabetics.3 We corresponded with researchers Dr. Al-Anouti and Dr. Al-Safar from Zayed University and Khalifa University to discuss their research on vitamin D receptor gene polymorphisms among Emirati patients with type 2 diabetes mellitus.Read More
DNA methylation (DNAm) has become increasingly widespread in the study of psychiatric disorders. Many psychiatric epigenetic studies began to work with peripheral tissues such as blood and saliva to determine which had the best correlation with brain tissue. Researchers like Smith et al compared the DNA methylation in post-mortem tissue samples with blood and saliva and found there was a higher correlation between the brain and saliva compared to blood - DNA methylation from saliva was about 3% more likely to agree with each area of the brain regions than DNA methylation with blood.1,Read More
Pharmacogenomics is a growing field that tailors dosage and drug choices based on patient genetic profiles with the potential to benefit millions of patients with personalized medical care while changing the world of medicine as we know it. One of the key obstacles faced by those working in pharmacogenomics is DNA sample collection. Traditionally, clinicians have used blood samples for DNA collection which are costly (requiring phlebotomy and cold chain logistics) and invasive (hindering patient compliance), making the clinical integration of pharmacogenomics difficult. Many researchers are turning to the idea of buccal and/or saliva swabs as a less costly and non-invasive alternative to DNA collection. However, the question is are these sample types of high enough quality for analysis?Read More
Since the launch of this blog, The Genetic Link, in 2009, we have published numerous articles, interviews, technical information and infographics to share what we know about DNA from saliva. Saliva is the human body’s most accessible bio-fluid but, after 7 years, we continue to be surprised at how often we hear wrong perceptions about this robust and easy to access sample type. It’s time to set the record straight on DNA from saliva once and for all. Are you ready? Here are 8 facts about DNA from saliva that most people don’t know.Read More
Russell Schachar, MD, FRCP(C), gave an engaging and inspiring talk at the American Society of Human Genetics (ASHG) conference this year titled: ADHD and OCD genetics: Populations, endophenotypes and quantitative traits.
The talk featured some of the exciting results gained from the large-scale Spit for Science project. Partnered with the Ontario Science Centre in Toronto, Canada, the Spit for Science project was initiated to accelerate discovery and further understanding of the nature of neurodevelopmental disorders, attention-deficit/hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD), in children. These types of disorders continue throughout life and can be extremely impairing.Read More
In this blog, we want to discuss the various genetic testing options available with respect to fertility and reproductive health; highlighting the sample collection methods often used to collect DNA. Genetic screening can be used to determine whether a person and/or their partner can successfully conceive a child or whether their infant is at risk to develop certain genetically-based conditions. Genetic risk factors can be passed through the DNA of either one or both parents during conception, and genetic screening helps identify abnormalities in the DNA or chromosomes that may be linked to unwanted health conditions.1 Genetic testing for fertility and reproductive health is being offered by a growing number of commercial companies and can be summarized into four main categories:Read More
Our knowledge of science is constantly changing and improving as new discoveries drive us forward in the modern world. Genomics is no exception. We witness these trends all around us either within the publications we read about new studies, in the news, or perhaps even through blogs such as this one. For example, I recently attended the American Society of Human Genetics conference in San Diego where I picked up a copy of Cell Press’s Trends Limited Edition High-Impact Genomics, Vol. 3 (link to document) which highlights particularly impactful genomics reviews. It captured my interest and I wanted to share a few highlights with you.Read More
The past decade of genetic advancements has proven DNA from saliva is reliable and effective for both research and diagnostics applications. The benefits of collecting DNA from saliva are clear:Read More