DNA Genotek's Sample Collection Blog

DNA Analysis in the Oklahoma Family Health Patterns Project

Posted by William R. Lovallo on Tue, Nov 22, 2011 @ 10:11 AM

Guest author, William R. Lovallo, Ph.D., is a Professor of Psychiatry and Behavioral Sciences and the Director of the Behavioral Sciences Laboratories at the University of Oklahoma Health Sciences Center and VA Medical Center, Oklahoma City OK. I hope you enjoy his story.

My lab is devoted to understanding the biological and psychological characteristics of persons at risk for alcoholism. Alcohol addiction is a behavioral disorder with both genetic and environmental contributions. Persons with a positive family history of alcoholism are 4 – 6 times as likely to develop an alcohol use disorder as persons with no such history. Our guiding hypothesis is that a genetic predisposition toward alcohol and other substance-use disorders involves altered function of brain regions regulating reward motivation. We are studying four domains of function related to prefrontal cortex and limbic system regulation of motivated behavior: 1) Behavioral under control: the person's temperamental balance of positive to negative affect should be less stable and weighted toward dysphoria.  2) Cognitive processing on tests or working memory.  3) Decision-making during a reward based delay discounting calling for choices between immediate, but small rewards vs. waiting over a time delay to gain a larger reward. 4) Visceral responses to psychological stress using the stress hormone, cortisol, and autonomic control of the heart.

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Tags: DNA collection, DNA saliva, SNP, Genome wide association studies, genetics and addiction

DNA Genotek presents new research at ASHG 2010

Posted by Shauna White on Wed, Nov 10, 2010 @ 14:11 PM

Last week, at the American Society for Human Genetics show in Washington, DC, several members of the DNA Genotek team presented posters reflecting new research findings. ASHG is an event that brings together over 5000 delegates from all areas of genetic research and is well known for encouraging and integrating research, scholarship and education in all areas of human genetics. We used this opportunity to showcase new research findings and technical evaluations for the Oragene family of products. 

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Tags: DNA saliva, CNV, DNA from saliva, Illumina, Genome wide association studies, Agilent

DNA Genotek's Top 10 List for 2009

Posted by Ian Curry on Mon, Jan 04, 2010 @ 14:01 PM

I have to admit, coming up with DNA Genotek's "Top 10 list for 2009" was more difficult than I imagined it would be. There are so many great things that happened in the past year - in our company, with our customers, and in the field of genetics - but I think I've narrowed it down to those that are most significant.

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Tags: DNA collection, DNA, DNA testing, DNA kit, DNA Kits, DNA saliva, Oragene, genetic disease, genetic testing, genotyping, Kaiser Permanente, DNA from animals, DNA dog kit, Genome wide association studies, genome mapping, GWAS, tropical disease

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This blog is intended to provide information to educate readers about molecular testing and genetic sample collection and DNA Genotek products.  Some of the information on this blog represents emerging scientific research or data developed for research purposes only. More information here.

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About DNA Genotek

Welcome to The Genetic Link, a blog providing new insights into DNA and RNA sample collection by DNA Genotek. DNA Genotek is a subsidiary of OraSure Technologies, Inc.

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