DNA Genotek's Microbiome Collection and Stabilization Blog

DNA Genotek's top 3 gut microbiome publication picks for 2018

Posted by Erin Carpenter on Dec 13, 2018 10:05:00 AM

It is no secret that gut microbiome research has been on the rise leading to a plethora of new insights, theories and discoveries. Like you – we’ve been absolutely captivated watching this burgeoning field evolve and introduce many new areas of advancement in theoretical understanding as well as direct therapeutic applications. There was certainly no shortage of exciting new publications in the gut microbiome field this year, and it was a challenge to narrow down our list – but we would like to share what we chose as our top three gut microbiome publication selections from 2018 with you.

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Tags: gut microbiome research, gut microbiome, omnigene gut

Collect and stabilize gut microbiota samples from IBD patients undergoing dysbiosis

Posted by Erin Carpenter on Nov 6, 2018 1:26:42 PM

In human gut microbiome studies, the logistics of immediately freezing and transporting collected stool samples on dry ice is not always feasible - especially with at-home collections. If the samples are not immediately stabilized, taxonomic profile changes can occur rapidly at room temperature. Furthermore, a challenge with collecting samples from patients exhibiting symptoms of inflammatory bowel disease (IBD) or Crohn’s and chronic colitis, is stool samples can be liquid (Bristol stool type 6 and 7), complicating collection and sample handling, as well as causing a barrier to donor enrolment. To facilitate large cohort studies and produce high quality data, researchers need to be equipped with the most effective tools to easily collect, stabilize and store precious samples.

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Tags: microbiome sample collection, gut microbiome research, feces collection

Varinos Inc. – Q&A with a Japanese biotech start-up

Posted by Erin Carpenter on Oct 10, 2018 1:21:00 PM

Readers of The Microbiome Snapshot know that we love to interview our customers and share what they learn from their research and clinical projects. Varinos Inc., an innovative biotechnology company based out of Japan, invited us to speak with them and learn about their unique work in the endometrial and vaginal microbiome. Recent research has shown the endometrial microbiota, the bacteria composition of the uterine lining, may influence female fertility and reproductive success. Using OMNIgene•VAGINAL microbiome kits for self-collection and stabilization of vaginal samples, Varinos is seeking to empower its customers and improve reproductive health.   

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Tags: microbiome sample collection, vaginal microbiome, OMNIgene Sputum, gut microbiome research

Microbiome research trends & highlights – interview with Aaron Del Duca

Posted by Erin Carpenter on Sep 25, 2018 1:48:00 PM

We had the opportunity to sit down with Aaron Del Duca, our VP Technology and Microbiome Program Lead to discuss a few trends in the microbiome field he’s most excited about. Aaron has spent the past 4 years engaging with scientists in academia and industry to understand what the biggest constraints to discovery are, and sharing insights and best practices at microbiome conferences and with standards organizations around the globe. Below, we’ve condensed Aaron’s take on five exciting developments and on-going challenges in the microbiome space.

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Tags: microbiome sample collection, microbiome standards, OMNIgene, gut microbiome research

Physical activity and the affect on maternal and fetal gut microbiome

Posted by Erin Carpenter on Aug 21, 2018 10:15:00 AM

Does physical activity affect the maternal and fetal gut microbiome? The University of Ottawa’s Placenta project could provide the answer. The placenta is a critical organ in pregnancy, providing a nutrient, oxygen and waste exchange interface between mother and fetus. Although this organ is essential to life, its role in optimal fetal health and development is not well understood. Kristi Adamo Ph.D., an Associate Professor in the School of Human Kinetics at the University of Ottawa, and her team are bridging this knowledge gap by focusing specifically on placenta research. In one on-going project, they are taking a multi-tiered approach to understanding the relationship between maternal physical activity and placenta biology.

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Tags: gut microbiome research, gut microbiome, omnigene gut, microbiome sample collection

Advances in microbiome discovery, diagnostics and therapeutics: Nature webcast highlights

Posted by Erin Carpenter on Aug 9, 2018 10:26:00 AM

Those of us following microbiome science know that it is developing extremely fast with tremendous opportunity for innovation. When we were presented the opportunity to participate in the recent webcast titled ‘Advances in Microbiome Discovery, Diagnostics and Therapeutics’ hosted by Nature.com, we were thrilled to agree. In this webinar, DNA Genotek and a panel of experts discussed their perspectives on advances in microbiome discovery. This webinar is available in its entirety on-demand (here), but knowing how time-pressed we all are, we have provided a summary for you below.

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Tags: gut microbiome research, microbiome, OMNIgene, microbiome collection

Choosing the best DNA extraction method in human gut microbiome community profiling

Posted by Erin Carpenter on Jul 30, 2018 9:06:00 AM

A critical component to any human gut microbiome study is the ability to accurately represent the ‘true’ microbial community present at a specific period in time or, in other words, a snapshot. With such a diverse sample type, there is considerable inter- and intra-subject variability, as well as methodological and technical sources of variation that can increase noise and obscure results. In this blog, we focus on discussing a technical source of variation – nucleic acid extraction methods. Read More

Tags: gut microbiome research, omnigene gut, DNA extraction

Microbiome highlights from Digestive Disease Week 2018

Posted by Erin Carpenter on Jul 5, 2018 9:51:00 AM

Digestive Disease Week 2018 (DDW2018) was another successful conference with over 450 sessions presented by invited speakers and abstract authors. The interest in how the microbiome could potentially impact digestive diseases grew even more this year as compared to past conferences, with more talks dedicated to the microbiome. Many of the talks were so popular they required overflow space in the hallways to accommodate all the interested audience members. You could feel the energy of new ideas being uncovered and knowledge being shared, and I felt privileged to be able to take part this year with a few of my fellow DNA Genotek colleagues.

With so many thought-provoking sessions to choose from, I certainly was not able to attend them all. With a particular interest in the gut microbiome, I wanted to share some of my highlights.

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Tags: gut microbiome research, omnigene gut, microbiome collection

Designing large-scale gut microbiome studies - 10 essential considerations

Posted by Erin Carpenter on Jun 12, 2018 9:51:00 AM

With a growing number of research studies showing associations between the gut microbiome and disease, this is a burgeoning field with fundamental questions that still need to be understood. The gut microbiome is composed of the community of microorganisms that dwell in our intestinal system, and elucidating the significance of this rich and diverse ecosystem is of great importance to human health. Large-scale studies with the sheer statistical power and immense volumes of data able to show strong correlations and draw meaningful conclusions are needed in this booming area of discovery.

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Tags: gut microbiome research, OMNIgene, microbiome stabilization, microbiome collection

DNA Genotek and the Mosaic Community Challenge: Standards

Posted by Aaron Del Duca on May 29, 2018 2:46:42 PM

If you are a frequent reader of The Microbiome Snapshot, you know that research into the human microbiome has emerged as highly informative to our overall understanding of health and disease risk. The growth in microbiome research has been fueled by many factors including the improvement of sequencing technologies and new computational methods. However, the impact of these methods have been somewhat limited by various factors such as precision, resolution, scalability and usability.

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Tags: gut microbiome research, gut microbiome, omnigene gut, microbiome standards

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This blog is intended to provide information to educate readers about microbiome sample collection, stabilization and DNA Genotek products. Some of the information on this blog represents emerging scientific research or data developed for research purposes only. More information here.

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About DNA Genotek

Welcome to The Microbiome Snapshot, a blog providing new insights into microbiome sample collection and stabilization by DNA Genotek. DNA Genotek Inc. is a subsidiary of OraSure Technologies, Inc.

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