DNA Genotek's Microbiome Collection and Stabilization Blog

Inspirational women in the microbiome field - International women's day

Posted by Katherine Lawless on Mar 8, 2019 8:32:00 AM

Throughout history women have influenced our views and knowledge of science from all disciplines, including microbiology. Through the co-development of an antitoxin for diphtheria by Dr. Anna Wessel Williams (1863-1954), grouping and typing of streptococci by Dr. Rebecca Craighill Lancefield (1895-1981), and the research on Haemophilus influenzae and Bordetella pertussis by a woman hailed as "woman scientist ahead of her time," Dr. Margaret Pittman (1902-1995), women have  influenced the study of microbiology.[1] The microbiome, a subset of microbiology, is a newer field and is rapidly advancing. Many of these advancements are being led by female scientists from all over the world.  

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Tags: gut microbiome research, microbiome analysis

Enabling big data and good data at the same time: The microbiome challenges CoreBiome was built to solve

Posted by Shauna White on Mar 4, 2019 1:24:00 PM

As a reader of The Microbiome Snapshot, you are likely aware that we recently acquired CoreBiome, a privately-held, Minnesota-based microbiome services provider that accelerates discovery for customers in the pharmaceutical, agricultural, and research communities. Many of you may also be aware of the strong reputation CoreBiome has as a leading service provider in the microbiome field – specifically for reducing costs while maximizing output for microbiome discovery.

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Tags: microbiome sample collection, microbiome extraction, microbiome analysis, shotgun sequencing

Why is an optimal DNA extraction important for microbial profiling?

Posted by Fatima Mahmood on Feb 12, 2019 1:31:00 PM

One of the many ways to ensure optimal isolation of bacterial DNA from stool samples, is through the use of an efficient extraction methodology. Our customers have been asking for extraction recommendations, so we conducted a validation study comparing four different manual extraction methods. There are many steps during the DNA isolation process where a multitude of biases can be introduced. The OMNIgene·GUT device reduces biases during stool sample collection to provide our users with an accurate snapshot of the in vivo gut microbial DNA content at the time of collection. This snapshot is maintained at ambient temperature for 60 days making it flexible and reliable to use when you are ready to extract microbial DNA.

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Tags: gut microbiome, omnigene gut, microbiome extraction

DNA Genotek's top 3 gut microbiome publication picks for 2018

Posted by Erin Carpenter on Dec 13, 2018 10:05:00 AM

It is no secret that gut microbiome research has been on the rise leading to a plethora of new insights, theories and discoveries. Like you – we’ve been absolutely captivated watching this burgeoning field evolve and introduce many new areas of advancement in theoretical understanding as well as direct therapeutic applications. There was certainly no shortage of exciting new publications in the gut microbiome field this year, and it was a challenge to narrow down our list – but we would like to share what we chose as our top three gut microbiome publication selections from 2018 with you.

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Tags: gut microbiome, omnigene gut, gut microbiome research

Collect and stabilize gut microbiota samples from IBD patients undergoing dysbiosis

Posted by Erin Carpenter on Nov 6, 2018 1:26:42 PM

In human gut microbiome studies, the logistics of immediately freezing and transporting collected stool samples on dry ice is not always feasible - especially with at-home collections. If the samples are not immediately stabilized, taxonomic profile changes can occur rapidly at room temperature. Furthermore, a challenge with collecting samples from patients exhibiting symptoms of inflammatory bowel disease (IBD) or Crohn’s and chronic colitis, is stool samples can be liquid (Bristol stool type 6 and 7), complicating collection and sample handling, as well as causing a barrier to donor enrolment. To facilitate large cohort studies and produce high quality data, researchers need to be equipped with the most effective tools to easily collect, stabilize and store precious samples.

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Tags: feces collection, gut microbiome research, microbiome sample collection

Varinos Inc. – Q&A with a Japanese biotech start-up

Posted by Erin Carpenter on Oct 10, 2018 1:21:00 PM

Readers of The Microbiome Snapshot know that we love to interview our customers and share what they learn from their research and clinical projects. Varinos Inc., an innovative biotechnology company based out of Japan, invited us to speak with them and learn about their unique work in the endometrial and vaginal microbiome. Recent research has shown the endometrial microbiota, the bacteria composition of the uterine lining, may influence female fertility and reproductive success. Using OMNIgene•VAGINAL microbiome kits for self-collection and stabilization of vaginal samples, Varinos is seeking to empower its customers and improve reproductive health.   

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Tags: gut microbiome research, vaginal microbiome, OMNIgene Sputum, microbiome sample collection

Microbiome research trends & highlights – interview with Aaron Del Duca

Posted by Erin Carpenter on Sep 25, 2018 1:48:00 PM

We had the opportunity to sit down with Aaron Del Duca, our VP Technology and Microbiome Program Lead to discuss a few trends in the microbiome field he’s most excited about. Aaron has spent the past 4 years engaging with scientists in academia and industry to understand what the biggest constraints to discovery are, and sharing insights and best practices at microbiome conferences and with standards organizations around the globe. Below, we’ve condensed Aaron’s take on five exciting developments and on-going challenges in the microbiome space.

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Tags: OMNIgene, gut microbiome research, microbiome standards, microbiome sample collection

Physical activity and the affect on maternal and fetal gut microbiome

Posted by Erin Carpenter on Aug 21, 2018 10:15:00 AM

Does physical activity affect the maternal and fetal gut microbiome? The University of Ottawa’s Placenta project could provide the answer. The placenta is a critical organ in pregnancy, providing a nutrient, oxygen and waste exchange interface between mother and fetus. Although this organ is essential to life, its role in optimal fetal health and development is not well understood. Kristi Adamo Ph.D., an Associate Professor in the School of Human Kinetics at the University of Ottawa, and her team are bridging this knowledge gap by focusing specifically on placenta research. In one on-going project, they are taking a multi-tiered approach to understanding the relationship between maternal physical activity and placenta biology.

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Tags: gut microbiome, omnigene gut, gut microbiome research, microbiome sample collection

Advances in microbiome discovery, diagnostics and therapeutics: Nature webcast highlights

Posted by Erin Carpenter on Aug 9, 2018 10:26:00 AM

Those of us following microbiome science know that it is developing extremely fast with tremendous opportunity for innovation. When we were presented the opportunity to participate in the recent webcast titled ‘Advances in Microbiome Discovery, Diagnostics and Therapeutics’ hosted by Nature.com, we were thrilled to agree. In this webinar, DNA Genotek and a panel of experts discussed their perspectives on advances in microbiome discovery. This webinar is available in its entirety on-demand (here), but knowing how time-pressed we all are, we have provided a summary for you below.

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Tags: microbiome, OMNIgene, microbiome collection, gut microbiome research

Choosing the best DNA extraction method in human gut microbiome community profiling

Posted by Erin Carpenter on Jul 30, 2018 9:06:00 AM

A critical component to any human gut microbiome study is the ability to accurately represent the ‘true’ microbial community present at a specific period in time or, in other words, a snapshot. With such a diverse sample type, there is considerable inter- and intra-subject variability, as well as methodological and technical sources of variation that can increase noise and obscure results. In this blog, we focus on discussing a technical source of variation – nucleic acid extraction methods. Read More

Tags: DNA extraction, omnigene gut, gut microbiome research

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This blog is intended to provide information to educate readers about microbiome sample collection, stabilization and DNA Genotek products. Some of the information on this blog represents emerging scientific research or data developed for research purposes only. More information here.

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About DNA Genotek

Welcome to The Microbiome Snapshot, a blog providing new insights into microbiome sample collection and stabilization by DNA Genotek. DNA Genotek Inc. is a subsidiary of OraSure Technologies, Inc.

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