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Best practices for improving next-generation microbiome sequencing

Dr. Daryl Gohl of the University of Minnesota Genomics Center, former CSO and founder of CoreBiome and current senior advisor to Diversigen, throughout his career has developed ...
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The impact of tobacco smoking on the oral microbiome

The oral microbiome is the second-largest and most diverse microbiota after the gut, harbouring over 700 species of bacteria. In The Microbiome Snapshot, we frequently cover ...
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Filling the microbiome data information gap

2020 so far has been an interesting year for me. I started the year by attending one of the biggest precision medicine conferences in the world, Precision Medicine World ...
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While social distancing, reaching donors shouldn’t be an issue

Governments and public health experts have advised almost everyone to stay home. The majority of the population is now working from home, while businesses and institutions are ...
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Validation of Diversigen's viral metagenomics sequencing and analysis pipeline for SARS-CoV-2 detection

This week we’re bringing you work from our co-workers at Diversigen, a science-driven company that specializes in customized solutions for metagenomics sequencing, ...
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Industry leaders Diversigen and CoreBiome come together to support microbiome discovery

As the microbiome industry grows and evolves, so has our team of microbiome experts. In 2019, DNA Genotek’s parent company, OraSure, acquired both CoreBiome and Diversigen. ...
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Strategies in microbiome sequencing

Choosing the best sequencing platform for your research There are many ways to profile a microbiome: Amplicon (16S) sequencing, shallow shotgun or deep shotgun. Each platform ...
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Standardization in microbiome measurements: considerations from sampling to analysis

UPDATE: On May 12, 2020, CoreBiome rebranded as Diversigen Inc. From sample collection to analysis, the ability to snapshot the microbial community and accurately analyze the ...
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The role of the microbiome in exploring childhood determinants of cardiovascular health

The Cardiovascular Risk in Young Finns Study is a prospective longitudinal study initiated in 1980. It is one of the largest follow-up studies into cardiovascular risk from ...
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Is there a new gold-standard for gut microbiome stool collection?

The “gold standard” for gut microbiome studies has traditionally been a fresh stool sample that was immediately processed or immediately frozen at -20ºC or -80ºC. However in ...
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PREdiCCt: the largest study on predicting IBD disease flare

This week, I interviewed Dr. Charlie Lees and Lee Murphy, investigators for the PREdiCCt Study (Prognostic effect of environmental factors in Crohn’s and Colitis). PREdiCCt is ...
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Sequencing the microbiome: Are you getting the full story?

Evolution of sequencing technology Since the human genome was sequenced and famously published in Nature and Science in 2001(1)(2), sequencing technology has experienced ...
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Cold chain stool sample collection: A series of unfortunate events (part 2/3)

Most people consider the nature of collecting fecal samples unpleasant and inconvenient. One of the challenges for the researcher conducting a gut microbiome study, is to ...
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Enabling big data and good data at the same time: The microbiome challenges CoreBiome was built to solve

UPDATE: On May 12, 2020, CoreBiome rebranded as Diversigen Inc. As a reader of The Microbiome Snapshot, you are likely aware that our parent company, OraSure, recently acquired ...
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Designing large-scale gut microbiome studies - 10 essential considerations

With a growing number of research studies showing associations between the gut microbiome and disease, this is a burgeoning field with fundamental questions that still need to ...
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Large population study highlights successful stool collection for microbiome analyses

The human microbiome is one of the hottest topics of interest in the scientific community. The microbes in and on a healthy human adult are estimated to at least equal the ...
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The importance of quality pre-analytical factors and their impact on microbiome analysis

Since the completion of the Human Microbiome Project (HMP), the number of microbiome focused research programs, peer-reviewed publications and patents has grown exponentially. ...
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