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The Mito-FIND project: Unlocking the secrets to mitochondrial disease with DNA from saliva

“Mitochondria are essential for life. Mitochondrial diseases interfere with the body’s ability to make energy and affect more than 2 million people in the world” - Mito-FIND ...
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Saliva as a sample type for genomic applications

This week, I interviewed Scott Rabuka, Director of the Genomics Program at DNA Genotek for our podcast, Molecules, Microbes and Multiomics. Scott joined DNA Genotek in 2008 as ...
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Genome-wide DNA methylation comparison: Brain tissue vs. blood, saliva and buccal cells

DNA methylation (DNAm) has become increasingly widespread in the study of psychiatric disorders.[1] Many psychiatric epigenetic studies began to work with peripheral tissues ...
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Is whole genome sequencing the new first-line test for children with genetic diseases?

Congenital anomalies and genetic disorders are the leading cause of death in children less than ten years old and affect about six percent of live births. For children with ...
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8 facts most people don’t know about DNA from saliva

Since the launch of this blog, The Genetic Link, in 2009, we have published numerous articles, interviews, technical information and infographics to share what we know about ...
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How to execute large-scale DNA sample collection for genetic research - 10 essential considerations

Genetic epidemiology, the study of how genetics contribute to health and disease in families and populations, seeks to derive a statistical analysis of how genetics works in ...
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High quality libraries for human WGS with direct saliva Input

In the open discussion webinar hosted by Frontline Genomics, Joshua Burgess Ph.D., Manager Scientific Research, R&D at Illumina and Rafal Iwasiow, Ph.D., Vice President, R&D at ...
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Discovering the genetics behind Ebola viral disease resistance

Phase I: DNA sample Collection The Ebola virus disease (EVD), formerly known as Ebola haemorrhagic fever, is a severe, often fatal illness in humans. The average EVD case ...
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The SPARK project – Fueling the fire on autism research

The Centers for Disease Control and Prevention (CDC) estimated in 2012 that 1 in 68 children in the US have autism spectrum disorder (ASD), (1 in 42 boys and 1 in 189 girls) [1]
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Oragene enables a large-scale array-CGH and exome sequencing study

In the summer of 2011 we wrote about an exciting project out of the United Kingdom that selected Oragene collection kits for a study that aimed to unlock genetic changes ...
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A quick guide to application compatibility for Oragene – PCR to NGS

In a recent article on The Genetic Link, we talked about going global and how our regulatory strategy helps support our customers who are conducting genetic research. Today, I ...
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Using NGS and DNA from saliva to find needles in haystacks

We always enjoy hearing about how our customers are using our products for innovative projects. Recently, we learned about a new project in Germany called GeneTalk, which uses ...
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Methodologies for the analysis of human exomes using DNA from saliva

Mike Tayeb is the Technical Support Manager at DNA Genotek Inc.
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The impact of bacterial DNA in saliva on whole genome sequencing

Mike Tayeb is the manager of technical support at DNA Genotek. 
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Reliability & stability of Oragene samples for WGS & exome sequencing

Rafal Iwasiow is Vice President of Research and Development at DNA Genotek.
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Genomic services now available direct from DNA Genotek

I am excited to tell you that today, at the America Society for Human Genetics conference, DNA Genotek launched a new service offering that we're very excited about. GenoFIND™ ...
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How to choose the right platform for high-throughput DNA extraction

We recently published an article highlighting how to choose the best method for low-throughput DNA extraction for Oragene samples. Today, we examine various options for ...
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[INFOGRAPHIC] DNA from saliva vs blood – who wins the cost battle?

Introducing DNA Genotek’s first visual adventure – a fun trip through the blood vs saliva cost journey. You and I know what they say, ‘A picture is worth a thousand words’ ...
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How to choose the best method for low-throughput DNA extraction

DNA is extracted from human saliva for a variety of reasons including molecular or forensic analysis. There are many benefits associated with collecting DNA from saliva with ...
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Can saliva replace blood for DNA collection and analysis? (Part 3 of 3)

Welcome to the final article in our 3 part series discussing whether or not saliva can replace blood for DNA collection and analysis. In part 1 and part 2 of this blog series, ...
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Can saliva replace blood for DNA collection and analysis? (Part 2 of 3)

Welcome to the second article in a 3 part series discussing whether or not saliva can replace blood for DNA collection and analysis. In part 1 of this blog series, we examined ...
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Can saliva replace blood for DNA collection & analysis? (Part 1 of 3)

Welcome to the first article in a 3 part series discussing whether or not saliva can replace blood for DNA collection and analysis. We hope you find this content interesting. ...
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Saliva samples as a source of DNA for high throughput genotyping

The BMC Medical Genomics Journal recently published the results of a study titled “Saliva samples are a viable alternative to blood samples as a source of DNA for high ...
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How confident are you in your oral DNA sample?

The first step in all genetic research and testing is obtaining a reliable DNA sample. The time and effort required to access donors and the high costs of downstream analysis ...
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DNA from saliva vs. blood – who wins the cost battle?

Collecting saliva DNA is more effective and less costly for genetic research, a study suggests. The study, titled Specimen Collection within the CRN: A critical appraisal, ...
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Further evidence – Next Gen Sequencing of DNA for Oragene/saliva samples

DNA from Oragene/saliva samples continues to gain acceptance as a suitable sample input for next generation sequencing technologies (NGS) from targeted to exome to whole ...
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DNA Analysis in the Oklahoma Family Health Patterns Project

Guest author, William R. Lovallo, Ph.D., is a Professor of Psychiatry and Behavioral Sciences and the Director of the Behavioral Sciences Laboratories at the University of ...
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UCLA team develops methylation-based model to predict age with Oragene

On June 22, 2011, Principal Investigator and professor of human genetics, pediatrics and urology at UCLA, Dr. Eric Vilain and his team of researchers revealed the results of ...
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Oragene•DNA Selected by Genomind for Personalized Medicine Test

Today,  DNA Genotek announced that our Oragene•DNA product has been selected by Genomind, LLC as the sample collection kit for the Genecept Mood™ Assay, a saliva-based ...
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3 reasons DNA from saliva is ideal for GWAS

With the growth of genome wide association studies (GWAS) and their need for DNA from many thousands of people, the time seemed right for us to highlight how DNA from saliva ...
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Oragene is a reliable source of DNA for next generation sequencing

This week, at Genomics Disorders 2011 in Cambridge, UK, DNA Genotek presented a poster reflecting new research findings. Building on the success of previous Genomic Disorders ...
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Oragene•RNA measures variability in gene expression for VITO

This morning, DNA Genotek announced an exciting piece of news. Our Oragene•RNA kit has been selected by VITO (Flemish Institute for Technological Research), for a series of ...
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DNA saliva samples for SNP and CNV analysis on microarrays

For any type of genetic analysis (e.g. population studies, clinical genetic testing, paternity testing, pharmacogenomic testing), non-invasive and easy-to-use sample ...
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Generation Scotland overcomes recruitment challenge with Oragene•DNA

At DNA Genotek, we recently learned the details of study being conducted by Generation Scotland called The Scottish Family Health Study. We wanted to share some of this ...
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Epigenetic change and gene inactivation demonstrated in the saliva of a cancer patient carrying an “epimutation of MLH1”.

The Genetic Link welcomes guest blog authors. This guest submission is from Megan P. Hitchins, PhD. Medical Epigenetics Laboratory, Lowy Cancer Research Centre, University of ...
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Research Study Validates Oragene•ANIMAL for Canine GWAS Studies

This month, PLoS ONE published a new research study that I think will interest readers of The Genetic Link. The study, titled "Array-Based Whole-Genome Survey of Dog Saliva ...
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Rinse, Swab or Spit -- What's the Real Source of DNA in Saliva?

Saliva is one of the most accessible of our body's bio-fluids making saliva sample collection easy and non-invasive. Saliva also harbours a wide spectrum of genetic data that ...
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Hunting for Cancer Genes with DNA from Saliva

Every day, it seems, scientists learn something new about how our genes work. One fascinating area of research involves understanding the role of our genes in the initiation, ...
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