DNA Genotek's Blog - The Genetic Link

Do you need an FDA cleared DNA collection device for your laboratory developed genetic test (LDT)?

By: Kathleen Weber on 09/18/19 9:51

If you are developing a genetic test that provides diagnostic information as part of a laboratory developed test (LDT) for use in the United States and were asked if you had to ...

DNA saliva kits or traditional blood collection: which is more cost effective?

By: Scott Rabuka on 05/22/19 13:26

Many researchers have asked the question: can saliva replace blood for DNA collection and analysis? Research studies confirm that DNA from saliva is equivalent to DNA from ...

Genome-wide DNA methylation comparison: Brain tissue vs. blood, saliva and buccal cells

By: Katherine Lawless on 04/03/19 13:30

DNA methylation (DNAm) has become increasingly widespread in the study of psychiatric disorders.[1] Many psychiatric epigenetic studies began to work with peripheral tissues ...

8 facts most people don’t know about DNA from saliva

By: Scott Rabuka on 02/01/19 10:25

Since the launch of this blog, The Genetic Link, in 2009, we have published numerous articles, interviews, technical information and infographics to share what we know about ...

Top 5 considerations when selecting a saliva-based DNA collection method

By: Kerry Chatburn on 10/10/18 10:09

The past decade of genetic advancements has proven DNA from saliva is reliable and effective for both research and diagnostics applications. The benefits of collecting DNA ...

How to execute large-scale DNA sample collection for genetic research - 10 essential considerations

By: Kerry Chatburn on 10/09/18 10:12

Genetic epidemiology, the study of how genetics contribute to health and disease in families and populations, seeks to derive a statistical analysis of how genetics works in ...

High quality libraries for human WGS with direct saliva Input

By: Erin Carpenter on 07/19/18 10:35

In the open discussion webinar hosted by Frontline Genomics, Joshua Burgess Ph.D., Manager Scientific Research, R&D at Illumina and Rafal Iwasiow, Ph.D., Vice President, R&D at ...

10 must-ask questions to help personal genomics companies get ahead

By: Kerry Chatburn on 02/28/17 11:07

Personal genomics is a branch of human genomics focused on sequencing and analyzing the unique genome of an individual to help determine optimal healthcare decisions… at least ...

Methodologies for the analysis of human exomes using DNA from saliva

By: Mike Tayeb on 07/11/13 9:34

Mike Tayeb is the Technical Support Manager at DNA Genotek Inc.

The impact of bacterial DNA in saliva on whole genome sequencing

By: Mike Tayeb on 06/07/13 10:18

Mike Tayeb is the manager of technical support at DNA Genotek.

HLA typing in Israel with Oragene and ORAcollect

By: Shauna White on 01/29/13 11:07

Approximately 30 years ago, the Tissue Typing Laboratory at the Sheba Medical Center in Israel was created to serve a newly launched cadaver-kidney organ sharing program. The ...

Reliability & stability of Oragene samples for WGS & exome sequencing

By: Rafal Iwasiow on 01/24/13 14:15

Rafal Iwasiow is Vice President of Research and Development at DNA Genotek.

10 hints to optimize DNA saliva samples, based on millions of samples

By: Mike Tayeb on 11/27/12 10:55

If there's one thing that makes us excited (other than saliva DNA samples, of course), it's seeing samples that are optimized to ensure the best possible results. Great DNA ...

How to choose the right platform for high-throughput DNA extraction

By: Krystin Colley on 09/26/12 14:46

We recently published an article highlighting how to choose the best method for low-throughput DNA extraction for Oragene samples. Today, we examine various options for ...

How to choose the best method for low-throughput DNA extraction

By: Krystin Colley on 08/07/12 11:21

DNA is extracted from human saliva for a variety of reasons including molecular or forensic analysis. There are many benefits associated with collecting DNA from saliva with ...

Can saliva replace blood for DNA collection and analysis? (Part 3 of 3)

By: Kerry Chatburn on 07/25/12 11:23

Welcome to the final article in our 3 part series discussing whether or not saliva can replace blood for DNA collection and analysis. In part 1 and part 2 of this blog series, ...

Can saliva replace blood for DNA collection and analysis? (Part 2 of 3)

By: Kerry Chatburn on 07/17/12 11:27

Welcome to the second article in a 3 part series discussing whether or not saliva can replace blood for DNA collection and analysis. In part 1 of this blog series, we examined ...

Can saliva replace blood for DNA collection & analysis? (Part 1 of 3)

By: Kerry Chatburn on 07/12/12 11:02

Welcome to the first article in a 3 part series discussing whether or not saliva can replace blood for DNA collection and analysis. We hope you find this content interesting. ...

Saliva samples as a source of DNA for high throughput genotyping

By: Shauna White on 07/03/12 10:32

The BMC Medical Genomics Journal recently published the results of a study titled “Saliva samples are a viable alternative to blood samples as a source of DNA for high ...

How confident are you in your oral DNA sample?

By: Kerry Chatburn on 06/05/12 11:16

The first step in all genetic research and testing is obtaining a reliable DNA sample. The time and effort required to access donors and the high costs of downstream analysis ...

DNA from saliva vs. blood – who wins the cost battle?

By: Scott Rabuka on 05/07/12 11:22

Collecting saliva DNA is more effective and less costly for genetic research, a study suggests. The study, titled Specimen Collection within the CRN: A critical appraisal, ...

Further evidence – Next Gen Sequencing of DNA for Oragene/saliva samples

By: Scott Rabuka on 04/05/12 10:39

DNA from Oragene/saliva samples continues to gain acceptance as a suitable sample input for next generation sequencing technologies (NGS) from targeted to exome to whole ...

UCLA team develops methylation-based model to predict age with Oragene

By: Shauna White on 06/27/11 14:40

On June 22, 2011, Principal Investigator and professor of human genetics, pediatrics and urology at UCLA, Dr. Eric Vilain and his team of researchers revealed the results of ...

The state of personalized medicine

By: Shauna White on 06/21/11 11:15

Last week at the Personalized Medicine Coalition’s (PMC) Annual State of Personalized Medicine Luncheon, John Castellani, President and CEO of the Pharmaceutical Research and ...

3 reasons DNA from saliva is ideal for GWAS

By: Shauna White on 04/05/11 13:20

With the growth of genome wide association studies (GWAS) and their need for DNA from many thousands of people, the time seemed right for us to highlight how DNA from saliva ...

Oragene is a reliable source of DNA for next generation sequencing

By: Rafal Iwasiow on 03/28/11 1:20

This week, at Genomics Disorders 2011 in Cambridge, UK, DNA Genotek presented a poster reflecting new research findings. Building on the success of previous Genomic Disorders ...

Challenges in DNA sample collection for personalized medicine

By: Shauna White on 03/01/11 13:41

We’ve been hearing the promises of personalized medicine for some time now with its magic formula of ‘the right treatment for the right patient at the right time’. In the past ...

HLA typing, transplants and Oragene (part 2)

By: Michael Gautreaux on 11/30/10 12:40

The Genetic Link welcomes guest blog authors. This guest submission is from Michael D. Gautreaux, Ph.D., an Associate Professor in the Department of General Surgery at Wake ...

HLA typing, transplants and Oragene (part 1)

By: Michael Gautreaux on 11/18/10 15:02

The Genetic Link welcomes guest blog authors. This guest submission is from Michael D. Gautreaux, Ph.D., an Associate Professor in the Department of General Surgery at Wake ...

DNA saliva samples for SNP and CNV analysis on microarrays

By: Rafal Iwasiow on 10/05/10 11:34

For any type of genetic analysis (e.g. population studies, clinical genetic testing, paternity testing, pharmacogenomic testing), non-invasive and easy-to-use sample ...

Generation Scotland overcomes recruitment challenge with Oragene•DNA

By: Shauna White on 08/31/10 13:08

At DNA Genotek, we recently learned the details of study being conducted by Generation Scotland called The Scottish Family Health Study. We wanted to share some of this ...

Easy & painless DNA collection for infants, children and non-spitters

By: Shauna White on 08/10/10 12:22

Genetic research into diseases and conditions that predominantly affect children has always been particularly challenging. Traditionally, when high quality and high quantity ...

Storage of Purified DNA from Oragene•DNA Samples

By: Scott Rabuka on 06/29/10 10:30

A few weeks ago, I posted an article about best practices for long term storage of unpurified Oragene•DNA samples on The Genetic Link. The response to the article was positive ...

Solving Recruitment and Compliance Challenges with DNA from Saliva

By: Shauna White on 06/09/10 10:15

The number of clinical trial and epidemiological studies collecting genomic DNA from a large number of individuals is increasing rapidly. There are many options for obtaining ...

Best Practices for Long-term Storage of Oragene•DNA Samples

By: Scott Rabuka on 05/25/10 10:57

Oragene is well known for a number of characteristics - ease of use, non-invasive collection, high quality and quantity DNA and, of course, long term storage at ambient ...

Rinse, Swab or Spit -- What's the Real Source of DNA in Saliva?

By: Brian Smith on 03/31/10 11:00

Saliva is one of the most accessible of our body's bio-fluids making saliva sample collection easy and non-invasive. Saliva also harbours a wide spectrum of genetic data that ...

7 Simple Steps to Maximize DNA Yield with Oragene•DNA

By: Scott Rabuka on 02/19/10 10:32

At DNA Genotek, we understand the importance of high quality DNA samples to support our customers' research and clinical studies. As a result, we work with our customers to ...

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